Microfluidic Cartridges
MFSI has developed a series of microfluidic cartridges for biological
sample processing and detection. Examples include: differential
extraction cartridges (see section on Patents Issued), sample
processing and amplification for biodefense applications, and
clinical sample processing and detection. The microfluidic
cartridge approach includes:
| Advantages |
Demonstrated Applications |
| Disposable |
| Environmental bacteria (e.g., E, coli) |
Biothreat agents |
| Easy to use |
| Clinical samples (Human Papiloma Virus) |
|
| Prevents sample to sample contamination |
|
Antibiotic resistant bacteria (e.g., MRSA) |
|
Portable |
Forensics such as differential extraction |
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Examples of MFSI’s Microfluidic Cartridges:
MFSI’s Differential Extraction Cartridge (Patent nos. 7,491,527, 7,553,647, and 7,553,647 B2). These patents are available for licensing. If interested contact: northrup@microfluidicsystems
MFSI’s Dragonfly Cartridge – provides cell lysis, nucleic acid purification, PCR amplification and fluorescent detection in less than 7 minutes on a 150 ul input sample. Proven applications include: environmental bacteria, human papiloma virus (HPV), and antibiotic resistant bacterial such as MRSA.
Gel verification results of the processing and amplification of a duplex HPV PCR assay from human cells on the Dragonfly cartridge. Processing and amplification time was fully automated and less than 7 minutes. |
